Phosphatidylserine (PS) is a phospholipid that plays a crucial role in cognitive functions and stress management. It is predominantly found in the brain, where it supports various nerve cell functions, including neurotransmitter production and synaptic activity. Research indicates that PS supplementation can enhance memory, alleviate stress, and potentially improve overall cognitive health, particularly in aging populations. The following sections delve into the specific benefits of phosphatidylserine.
Memory Enhancement
- PS has been shown to improve memory abilities, particularly in non-demented elderly individuals with memory complaints. A study demonstrated that PS containing omega-3 fatty acids could enhance memory performance in this demographic (Vakhapova et al., 2010).
- In animal models, PS supplementation has been linked to improved cognitive functions and a delay in age-related cognitive decline, suggesting its potential in mitigating Alzheimer’s disease symptoms (Kim & Park, 2020).
Stress Support
- PS is known to modulate the body’s response to stress. It has been observed to support the hypothalamic-pituitary-adrenal axis, which is crucial for managing stress responses (Kidd, 1996).
- A study involving healthy men indicated that PS-rich phospholipid concentrate might improve working memory and reduce reaction times under stress, although endocrine stress responses did not significantly differ from placebo (Hellhammer et al., 2010).
Anti-Aging and Oxidative Stress
- PS supplementation has been associated with increased resistance to oxidative stress and extended lifespan in model organisms like C. elegans. This effect is partly due to its role in reducing insulin/IGF-1-like signaling and requiring DAF-16, a transcription factor involved in stress response (Kim & Park, 2020).
As research continues to highlight the cognitive and stress-supporting potential of phosphatidylserine, the focus is now shifting to the quality, source, and formulation of PS used in supplements. This is where ECA Healthcare delivers value by providing a diverse portfolio of premium phospholipids designed for clean-label, sustainable, and high-performance formulations. From soya- and sunflower-derived phosphatidylserine to innovative sn-2 structured phospholipids, our ingredient range supports product developers in creating evidence-based solutions that meet both regulatory and consumer expectations.
ECA’s PREMIUM PHOSPHOLIPIDS PROFILE >>
Phosphatidylserine (PS) Series
Phosphatidylcholine (PC) Series
Other Phospholipids
Phosphatidylinositol (PI)
Phosphatidic Acid (PA)
Phosphatidylethanolamine (PE)
Soy Lecithin Liquid & Powder
Sunflower Lecithin Liquid & Powder
Innovative Grade : MoleQ® PS – Water-soluble Phosphatidylserine
